Kylie quinn in Qingdao - Robust estimation of bacterial cell count from optical density

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In kylie Qingdao quinn Robust estimation

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It is unclear the degree to which this is due to known issues of CFU, such as cells adhering into clumps, as opposed to the problems with imprecision noted above or yet other possible unidentified causes.

  • Gene expression typically has a log-normal distribution , meaning that bulk measurements will be distorted upward compared to the geometric mean of log-normal distribution observed with the single-cell measurements of a flow cytometer.

  • With the microsphere protocol, on the other hand, some failures such as systematic dilution error and instrument saturation can not only be detected, but also modeled and corrected for.




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